Pervasive population genomic consequences of genome duplication in Arabidopsis arenosa

Monnahan, Patrick; Kol�?, Filip; Baduel, Pierre; Sailer, Christian; Koch, Jordan; Horvath, Robert; Laenen, Benjamin; Schmickl, Roswitha; Paajanen, Pirita; �r�mkov�, Gabriela; Bohut�nsk�, Magdalena; Arnold, Brian; Weisman, Caroline M.; Marhold, Karol; Slotte, Tanja; Bomblies, Kirsten; Yant, Levi

Abstract

Ploidy-variable species allow direct inference of the effects of chromosome copy number on fundamental evolutionary processes. While an abundance of theoretical work suggests polyploidy should leave distinct population genomic signatures, empirical data remains sparse. We sequenced ~300 individuals from 39 populations of Arabidopsis arenosa, a naturally diploid-autotetraploid species. We find the impacts of polyploidy on population genomic processes are subtle yet pervasive, including reduced efficiency of purifying selection, differences in linked selection, and rampant gene flow from diploids. Initial masking of deleterious mutations, faster rates of nucleotide substitution, and interploidy introgression likely conspire to shape the evolutionary potential of polyploids.

Citation

Monnahan, P., Kolář, F., Baduel, P., Sailer, C., Koch, J., Horvath, R., …Yant, L. (2019). Pervasive population genomic consequences of genome duplication in Arabidopsis arenosa. Nature Ecology and Evolution, 3(3), 457-468. https://doi.org/10.1038/s41559-019-0807-4

• Journal Article Type: Article
• Acceptance Date: Jan 10, 2019
• Online Publication Date: Feb 25, 2019
• Publication Date: Mar 1, 2019
• Deposit Date: Feb 26, 2019
• Publicly Available Date: Aug 26, 2019
• Journal: Nature Ecology and Evolution
• Electronic ISSN: 2397-334X
• Publisher: Nature Research
• Peer Reviewed: Peer Reviewed
• Volume: 3
• Issue: 3
• Pages: 457-468
• DOI: https://doi.org/10.1038/s41559-019-0807-4
• Public URL: https://nottingham-repository.worktribe.com/output/1584348
• Publisher URL: https://www.nature.com/articles/s41559-019-0807-4
• Contract Date: Feb 26, 2019